It's Time TO CHALLENGE
Our Understanding of TDT
 

Transfusion-Dependent β-Thalassemia (TDT) is a severe, progressive,
genetic disease that impacts patients for life.1,2
Transfusion-Dependent β-Thalassemia (TDT) is a severe, progressive, genetic disease that impacts patients for life.1,2

TDT is the most severe form of beta-thalassemia, characterized by severe anemia
and lifelong transfusion dependence which leads to iron overload, and can result in
serious comorbidities and reduced survival. It's time to challenge our understanding
of TDT and consider its genetic defect when caring for patients with
beta‑thalassemia.1,2,3
TDT is the most severe form of beta-thalassemia, characterized by severe anemia and lifelong transfusion dependence which leads to iron overload, and can result in serious comorbidities and reduced survival. It's time to challenge our understanding of TDT and consider its genetic defect when caring for patients with beta‑thalassemia.1,2,3

There is an opportunity to explore additional options
that can correct the genetic defect in TDT.

Patients with TDT require lifelong transfusions for survival1

Chronic transfusion therapy enables survival, but only intermittently addresses symptoms and can lead to serious complications.1

 

Allogeneic HSCT can potentially correct the genetic deficiency in TDT1,4,5

While it may give patients the opportunity to be thalassemia-free, HSCT is mostly limited to pediatric patients with HLA-matched donors.1,4,5

 

Quality of life is significantly compromised in patients with TDT6,7

Lifelong dependency on transfusions and ongoing supportive care can be physically and psychologically demanding on beta-thalassemia patients and caregivers.6,7

Register now to receive resources to help support
your TDT patients, invites
to future webinars, and
additional information about beta‑thalassemia.
Life with beta-thalassemia
Help patients better understand the current impact TDT has on their lives, set goals,
and plan for the future.
Help patients better understand the current impact TDT has on their lives, set goals, and plan for the future.
man walking

Actor portrayals throughout. Not real patients

Take the
Beta-Thalassemia
Challenge

Current Thalassaemia International Federation (TIF) treatment guidelines for transfusion-dependent beta-thalassemia (TDT) recommend that:

Actor portrayals throughout. Not real patients